Stem Cell Therapy for Premature Ovarian Insufficiency

Premature Ovarian Insufficiency (POI) is the condition of ovaries and insufficiency to produce eggs. This condition is treatable through different hormone replacement therapies and medications, but Stem Cell Therapy stays the best available treatment option for premature ovarian insufficiency.

POI occurs as a result of inhibition ovarian function in women before the age of 40 years. When this condition happens, women's ovaries can't produce new eggs and hormones like estrogen. This condition is also referred to as infertility or premature ovarian failure. POI and menopause aren't the same things because menopause is a normal phenomenon with the advancing age.

The most common causes of POI are:

Chromosomal changes – genetic disorders (fragile X syndrome and mosaic turner syndrome)

Toxins production

Autoimmune response to the disease

Idiopathic factors

The most significant risk factors for Premature Ovarian Insufficiency (POI) are:

Ovarian surgeries

Family history of ovarian insufficiency

Age between 35-40 years and more

The most common sign and symptoms of the POI are:

Night sweats

Difficulty concentrating and irritability

Difficulty in getting pregnant

Irregularity in periods and menstruation

Dry eyes

Vaginal dryness

Hot flashes

THE TREATMENT JOURNEY

The vital cause of PO I is estrogen insufficiency. So, the treatment of the disease consists of:

Estrogen therapy – to prevent osteoporosis and estrogen deficiency. Moreover, the addition of progesterone also aids in the protection of the uterus lining

Hormone replacement therapies

Medications

Vitamin D (600-800 international units per day) and Calcium supplements (1,000 milligrams). Both calcium and vitamin D have vital significance in preventing adverse effects of POI in the female body.

Stem Cells are the natural repair process of your body parts. SCs are present in our fat cells, bone marrow cells, and in this case, we use Mesenchymal Stem Cells from donor cord blood. If you place the stem cells over the area of damage, then these cells can lead to the activation of new and healthy cells. This healing process is what our body needs. Stem Cell Therapy helps boost body repair mechanisms and introduces new Stem Cells.

Stem Cell Therapy is a novel practice for the treatment of different conditions which are otherwise difficult to treat. In premature ovarian insufficiency, Stem Cell Therapy or Mesenchymal Stem Cell can help in restoring ovarian functions and can lead to the production of oocytes (immature cells). According to the ultrasound examinations, Mesenchymal Stem Cells have evidence of improved endometrial thickness and ovarian size. The success rate of Stem Cell Therapy for premature ovarian failure is up to 80% in most patients.

The Stem Cell Therapy (SCT) at The Renue Centre is a holistic approach to treating Sexual Wellness

Your Renue Journey for Premature Ovarian Insufficiency (POI) with Stem Cells consists of four phases:

Pre-treatment: You will take our Renue Epigenetic Test powered by TruDiagnostics, which will assert your biological age and other important health markers. Your TruDiagnostics test is part of The Renue Difference. It provides your doctor with critical information about your health and your true age (biological vs chronological).

 After the epigenetic test and we have received all your medical records, your Patient Advisor will assist you in planning your travel to Puerto Vallarta.

Treatment day: the treatment starts with taking a specific amount of blood through apheresis. After taking the Stem Cells, the rest of the blood is returned to the donor.

30, 60 & 90 days follow up: POI symptoms clinical evaluation to check for flare-up frequency, improvements, pain, and irritation.

6 months after treatment: POI symptoms clinical evaluation lab tests, flare-up frequency, clinical evaluation, mobility, quality of life, and prognosis.

The effectiveness of Stem Cell Treatment can improve all your symptoms, causing a considerable impact on your quality of life and daily activities.

As part of The Renue Difference, you will receive three Hyperbaric Chamber sessions that greatly improve SCT efficacy and stimulate the body cells to combat Premature Ovarian Insufficiency. These sessions comprise three days: one day before treatment, after treatment, and on the day of treatment.

According to results, clinical outcomes, and pre-and post-treatment observations, SCT has been shown to help

Reduce Premature Ovarian Insufficiency progression

Speed up tissue repair

Regrow and repair tissues after six months

After the SCT procedure, an MRI test depicts the further need for the treatment at a specific body site.

Talk to our Patient Advisor to know more about SCT at The Renue Medical Centre.

Improved infertility in women

More chances of conception and perception

Maturation of ovulation for conception and pregnancy immediately after the treatment

Improved quality of life and satisfaction

FREQUENT QUESTIONS

Generally, Stem Cell Therapy has a satisfactory safety profile, good prognosis, and effectiveness.

However, no medical procedure is 100% safe; so, the most frequent or common risk factors of SCT can be:

Lethargy and fatigue

Allergic reactions

Bleeding from the site of injection

Fever

Painful injection area /site

Pre-treatment education can help with awareness of slight side effects of the therapy. Allergic reactions are preventable through pre-injection history and care. Bleeding and swelling of the injured site is manageable via proper technique. Fever, lethargy, and pain are managed through the appropriate drugs along with the treatment.

Stem Cell Therapy is a new and promising method of treating Premature Ovarian Insufficiency. It has the potential to be more effective than previous methods and also carries less risk. At present, stem cell technology is still in the developmental stage, but rapid developments and advances indicate its potential uses in direct treatments of Premature Ovarian Insufficiency.

The benefits and effects of Stem Cell Therapy depend on several factors: the patient's health condition, underlying issues, lifestyle, and others.

To assess your expected results, we would like to know more about you.

A medical advisor will talk to you about your diagnosis and treatment options and collect information for the attending physician; they can answer all your initial questions:

Will the therapy work for my case?

What does the treatment involve? Is it painful?

Is it expensive? How much does it cost?