RENUE: Elevate Your Quality of Life

Musculoskeletal Disorders

Stem Cell Therapy for Back Disorder

MSC therapy to support disc and soft tissue repair for chronic back conditions.

What is a Back Injury?

Back injuries (BI) refer to damage to the muscular or skeletal systems, typically caused by strenuous activity. These injuries affect bones, muscles, ligaments, nerves, or tendons, resulting in pain.

What causes a Back Injury?

Back injuries (MSIs) involve damage to bones, muscles, ligaments, and nerves, and are highly prevalent. As you age, the likelihood of experiencing these injuries increases.

Back pain can arise suddenly or develop gradually, sometimes becoming long-lasting. This pain encompasses a range of conditions and can result from dislocations (when a joint is pushed out of its natural alignment), repetitive stress injuries, strains, fractures, and postural dysfunctions.

How are Back Disorders commonly treated?

The backbone, or spine, is a crucial structure that supports your body, enabling you to walk, bend, and move. It connects various parts of the musculoskeletal system, while the surrounding musculature helps maintain balance and trunk movement. Injuries to the back, spinal cord disorders, and other issues can damage the spine, leading to back discomfort.

Treatment includes:

Medications: Back pain often requires prescription drugs, as over-the-counter NSAIDs may not be effective.

Physical Therapy: Techniques such as transcutaneous electrical nerve stimulation (TENS), heat and cold therapy, therapeutic ultrasound, and myofascial release can effectively relieve back pain.

Complementary Therapies: Shiatsu, yoga, and chiropractic care can help alleviate back discomfort.

Surgery: Surgical options include spinal fusion, vertebrae removal, and discectomy.

What Is Stem Cell Therapy?

Stem cells are integral to the body's natural repair processes. They are present in fat cells and bone marrow cells, and in this case, we use mesenchymal stem cells (MSCs) from donor cord blood. When applied to damaged areas, these stem cells activate the growth of new, healthy cells, facilitating the body's healing process. Stem Cell Therapy enhances the body's repair mechanisms by introducing new stem cells.

How Do Stem Cells Work on Back Injuries?

Back injuries (BI) can be caused by various factors, such as overstretching tissue, inflammation, athletic activities, overuse, and the natural aging process. Stem Cell Therapy is particularly effective for treating long-term illnesses and injuries that are difficult to cure, such as MSIs. By supporting the body's natural healing processes and generating new cells, Stem Cell Therapy has the potential to restore damaged tissue.

Stem cells have a remarkable ability to self-renew and differentiate into any cell type. This capacity allows them to transform into other tissues and regulate the immune system's response, promoting faster regeneration and recovery of muscles, connective tissues, and bones.

What are the Back Immune Response Issues?

Studies have shown that regeneration and repair processes are regulated by a complex interaction between the immune system and the musculoskeletal system. When tissue rupture occurs, it triggers a cascade of reactions involving both systems.

Initially, an inflammatory response is generated, beginning with neutrophils and followed by macrophages. The production of anti-inflammatory cytokines and the activity of macrophages are crucial for the regeneration and growth of disrupted tissues in the musculoskeletal system. The immune response to Back injuries varies between the acute and chronic phases due to the differing roles of macrophages.

Stem cell therapy for Back Disorder at Renue

How can Stem Cell Therapy treat Back Injuries?

Mesenchymal Stem Cells (MSCs) are adult stem cells with the ability to self-renew. In musculoskeletal injuries, MSCs repair and preserve damaged cells by replacing compromised and malfunctioning cells with healthy tissue. They work by naturally activating and releasing an anti-inflammatory response, thereby reducing pain. MSCs also produce healthy blood cells that aid in repair, particularly in tissues with insufficient blood flow, such as tendons, cartilage, and ligaments. This process results in improved functional ability, pain relief, and the repair of damaged tissues, with the ultimate goal of minimizing the need for surgery by reducing pain and enhancing functionality.

Exosomes and Back disorders

Stem Cell Therapy and Exosomes offer an effective treatment for Back disorders, leveraging the vital role of microRNAs (miRNAs) in disease prevention and progression. One common issue in musculoskeletal disorders is cartilage destruction, which can be mitigated by silencing miRNA-101 through exosomes, helping to prevent cartilage degradation in arthritis.

Another significant benefit of MSC-Exosome Therapy is promoting osteoclast differentiation and bone-forming cell proliferation. Studies have shown that exosomes can protect against acute tubular injuries by mediating cell interactions and stimulating cell proliferation, thereby aiding in the control of various diseases and traumas.

How is the treatment at The Renue Medical Centre different?

The Stem Cell Therapy (SCT) at The Renue Centre is a holistic approach to treating Musculoskeletal Problems.

Your Renue Journey for Back Repair with Stem Cells consists of four phases:

Pre-treatment: You will take our Renue Epigenetic Test powered by TruDiagnostics, which will assert your biological age and other important health markers. Your TruDiagnostics test is part of The Renue Difference. It provides your doctor with critical information about your health and your true age (biological vs chronological). After the epigenetic test and we have received all your medical records, your Patient Advisor will assist you in planning your travel to Puerto Vallarta.

Treatment day: On the treatment day, a specific amount of blood is taken through apheresis to activate the Stem Cells for administration. A total of 100 million umbilical cord-mesenchymal Stem Cells are inserted in one sitting through the IV route; in addition, 4 injections of 25 Million around the affected area of the back.

30, 60 & 90 days follow-up: To check for flare-up frequency, improvements, pain, and irritation

Six months after treatment: Lab tests, flare-up frequency, clinical evaluation, mobility, quality of life, and prognosis

Expected results: benefits and outcomes

SCT to live a better life: Benefits and outcomes

The effectiveness of Stem Cell Treatment can improve all your symptoms, causing a considerable impact on your quality of life and daily activities.

As part of The Renue Difference, you will receive three Hyperbaric Chamber sessions that greatly improve SCT efficacy and stimulate the body cells to treat MSIs in the back. These sessions comprise three days: one day before treatment, after treatment, and on the day of treatment.

According to results, clinical outcomes, and pre and post-treatment observations, SCT has been shown to help

Reduce MSIs progression

Speed up tissue repair

Regrow and repair tissues after six months

After the SCT procedure, an MRI test depicts the further need for the treatment at a specific body site.

Talk to our Patient Advisor to know more about SCT at The Renue Medical Centre.

Expected results and prognosis:

Back disorders are one of the most consulted diseases, and their treatment can get complex sometimes.

Stem Cell Therapy has shown positive outcomes in the treatment of musculoskeletal back conditions, divided into the following phases:

Prognosis I: Instant benefit achieved in the first-week post-treatment is reduced pain and inflammatory symptoms

Prognosis II: Approximately three months after Stem Cell Therapy, patients will experience improvement in trunk and back mobility as well as achieve a partial to complete range of motion. Pain with back mobility will also decrease

Prognosis III: In the chronic phase of recovery, six months post-treatment, patients' quality of life improves, and mobility continues to enhance, resulting in independence in daily life activities

What are the risk factors of Stem Cell Therapy for Musculoskeletal Injuries and conditions?

Despite the potential therapeutic promise of Stem Cell-based treatments, there are still some risk factors with this treatment. Before using stem cells in a therapeutic setting, it's important to assess the risk factors.

Some of the risk factors are:

Harmful reactions in the area of administration

Formation of benign tumors

Stem cells can travel from the site of injection to other areas of the body and possibly reproduce into harmful cells and multiply

Stem cells might not operate the way they are expected

Management of risks

The majority of the adverse outcomes and side effects are manageable. Wounds and any bleeding from the treatment area must be properly managed in diabetic individuals. Infections and inflammation can be treated with over-the-counter drugs, which can help reduce adverse effects. A thorough pre-and post-operative preparation program helps you avoid and control all of the risks involved with Stem Cell Treatment.

This page is for general information and does not constitute medical advice. All treatment plans at Renue are individualized following a physician review. See Research Articles for supporting literature.

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Hyperbaric Oxygen Center

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